IBS Life Science Institute

RNA stability enhancers for durable base-modified mRNA therapeutics

Soo-Jin Jung, Jenny J. Seo, Sunghan Lee, Seong-In Hyun, Ji-eun Lee, Sojeong Lee, Yeji Lee, Hyeshik Chang, Hyukjin Lee, Jin-Hong Kim, V. Narry Kim [NATURE BIOTECHNOLOGY (November, 2025)]

ERH promotes primary microRNA processing beyond cluster assistance

Harim Jang, Junyoung Park, V Narry Kim [NATURE COMMUNICATIONS 16(1)(August, 2025)]

Intracristal space proteome mapping using super-resolution proximity labeling with isotope-coded probes

Myeong-Gyun Kang, Sanghee Shin, Dong-Gi Jang, Ohyeon Kwon, Song-Yi Lee, Pratyush Kumar Mishra, Minkyo Jung, Ji Young Mun, Jung-Min Kee, Jong-Seo Kim, Hyun-Woo Rhee [NATURE COMMUNICATIONS 16(1)(August, 2025)]

Human cytomegalovirus long non-coding RNA counteracts nuclear cGAS to facilitate immune evasion

Sungwon Lee, Sungchul Kim, Hyejun Kim, Dohoon Lee, Dongjoon Jeong, Hyewon Kim, Junhyun Park, Kiwon Park, Jin Hur, Sun Kim, V Narry Kim, Kwangseog Ahn [NATURE MICROBIOLOGY 10(9)(September, 2025)]

Gene expression dynamics before and after zygotic gene activation in Drosophila early embryogenesis

Yongwoo Na, Yeon Choi, Thi Thanh My Nguyen, Hoang-Anh Pham-Bui, Jeesoo Kim, V Narry Kim, Mihye Lee, Jong-Seo Kim [ISCIENCE 28(9)(September, 2025)]

SARS-CoV-2 Nsp2 recruits GIGYF2 near viral replication sites and supports viral protein production

Jimi Kim, Youngran Park, Doil Yoon, Sunghan Lee, Haedong Kim, Ka-Yun Ban, Jihye Yang, Da-Eun Choi, Jeesoo Kim, Jong-Seo Kim, V Narry Kim [NUCLEIC ACIDS RESEARCH 53(14)(August, 2025)]

3AIM-seq: Quality assessment of mRNA therapeutics using sequencing for 3′ poly(A) tails of in vitro-transcribed mRNA

Jina Seo, Hyo-Jung Park, Ayoung Oh, Chang Beom Jeong, Sohee Kim, Sojeong Lee, Chuna Kim, Hyeshik Chang, Jae-Hwan Nam, Daechan Park [Molecular Therapy 33(10)(June, 2025)]

N6-methyladenosine modification of HCMV IE1 transcript promotes the repressive state of viral genome to achieve latent infection

Heena Jeong, Nagyeong Yeo, Hyeonseo Hwang, Junhyun Park, Daehyun Baek, Kwangseog Ahn [PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 122(24)(June, 2025)]