IBS Life Science Institute

Aptamer-Guided, Hydrolysis-Resistant Deoxyoxanosine Enables Epitope- and Moiety-Selective Conjugation to Nonengineered Proteins Even in Complex Environments

Hyesung Jo, Seonmin Ju, Minhye Kim, Jiyun Beon, Se-Young Jang, Seung Pil Pack, Chang Yun Son, Jong-Seo Kim, Seung Soo Oh [JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 147(11), 9328-9340(March, 2025)]

Regulation of senescence-associated secretory phenotypes in osteoarthritis by cytosolic UDP-GlcNAc retention and O-GlcNAcylation

Donghyun Kang, Jeeyeon Lee, Geunho Yook, Sehan Jeong, Jungkwon Shin, Mi-Sung Kim, Yi-Jun Kim, Hyeryeon Jung, Jinsung Ahn, Tae Woo Kim, Moon Jong Chang, Chong Bum Chang, Seung-Baik Kang, Won Ho Yang, Yong-Ho Lee, Jin Won Cho, Eugene C Yi, Chanhee Kang, Jin-Hong Kim [NATURE COMMUNICATIONS 16(1), 1094-(February, 2025)]

Autophagy-dependent splicing control directs translation toward inflammation during senescence

Jaejin Kim, Yeonghyeon Lee, Taerang Jeon, Seonmin Ju, Jong-Seo Kim, Mi-Sung Kim, Chanhee Kang [DEVELOPMENTAL CELL 60(3), 364-378(February, 2025)]

Another common genetic ataxia in South Korea: Spinocerebellar ataxia 36

Jong Hyeon Ahn, Seungbok Lee, Jangsup Moon, Yoojung Han, Hyeshik Chang, Jinyoung Youn, Jin Whan Cho & Ja-Hyun Jang [EUROPEAN JOURNAL OF HUMAN GENETICS (February, 2025)]

Secreted LGALS3BP facilitates distant metastasis of breast cancer

Seung-Su Kim, Issac Park, Jeesoo Kim, Na-Lee Ka, Ga Young Lim, Mi-Ye Park, Sewon Hwang, Ji-Eun Kim, So Yeon Park, Jong-Seo Kim, Hyun-Woo Rhee, Mi-Ock Lee [BREAST CANCER RESEARCH 27(1), 4-(January, 2025)]

Human immunodeficiency virus-1 induces host genomic R-loops and preferentially integrates its genome near the R-loop regions

Kiwon Park, Dohoon Lee, Jiseok Jeong, Sungwon Lee, Sun Kim, Kwangseog Ahn [eLife (December, 2024)]

miR-124 coordinates metabolic regulators acting at early stages of human neurogenesis

Geurim Son, Yongwoo Na, Yongsung Kim, Ji-Hoon Son, Gregory D Clemenson, Simon T Schafer, Jong-Yeon Yoo, Sarah L Parylak, Apua Paquola, Hyunsu Do, Dayeon Kim, Insook Ahn, Mingyu Ju, Chanhee S Kang, Younghee Ju, Eunji Jung, Aidan H McDonald, Youngjin Park, Gilhyun Kim, Se-Bum Paik, Junho Hur, Joon Kim, Yong-Mahn Han, Seung-Hee Lee, Fred H Gage, Jong-Seo Kim, Jinju Han [COMMUNICATIONS BIOLOGY 7(1), 1393-(October, 2024)]

C-TERMINAL DOMAIN PHOSPHATASE-LIKE 1 promotes flowering with TAF15b by repressing the floral repressor gene FLOWERING LOCUS C

Jinseul Kyung, Daesong Jeong, Hyunjoo Eom, Jeesoo Kim, Jong-Seo Kim, Ilha Lee [Molecules and cells 47(10)(October, 2024)]