IBS Life Science Institute

Structural basis of the catalytic and allosteric mechanism of bacterial acetyltransferase PatZ

Jun Bae Park, Gwanwoo Lee, Yu-Yeon Han, Dongwook Kim, Kyoo Heo, Jeesoo Kim, Juhee Park, Hyosuk Yun, Chul Won Lee, Hyun-Soo Cho, Jong-Seo Kim, Martin Steinegger, Yeong-Jae Seok, Soung-Hun Roh [PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 122(24)(June, 2025)]

Mitochondrial fumarate inhibits Parkin-mediated mitophagy

Su Jin Ham, Sunhoe Bang, Daihn Woo, Jae-Yoon Jo, Takwon Yoo, Eunju Yoon, Yeonju Kyoung, Daehyun Baek, Jong-Seo Kim, Jongkyeong Chung [Molecular Cell 85(12), 2287-2302.e9(June, 2025)]

SLIRP amplifies antiviral signaling via positive feedback regulation and contributes to autoimmune diseases

Doyeong Ku, Yewon Yang, Youngran Park, Daesong Jang, Namseok Lee, Yong-ki Lee, Keonyong Lee, Jaeseon Lee, Yeon Bi Han, Soojin Jang, Se Rim Choi, You-Jung Ha, Yong Seok Choi, Woo-Jin Jeong, Yun Jong Lee, Kyung Jin Lee, Seunghee Cha, Yoosik Kim [CELL REPORTS 44(5)(May, 2025)]

Human cytomegalovirus infection induces L1 expression through UL38-dependent mTOR-KAP1 pathway

Sehong Park, Jiseok Jeong, Kwangseog Ahn [PLoS ONE 20(4), e0320512-(April, 2025)]

Mechanisms of chemotherapy failure in refractory/relapsed acute myeloid leukemia: the role of cytarabine resistance and mitochondrial metabolism

Soo Yeon Chae, Se-Young Jang, Jinhui Kim, Sehyun Hwang, Disha Malani, Olli Kallioniemi, Seung Gyu Yun, Jong-Seo Kim, Hugh I Kim [CELL DEATH & DISEASE 16(1), 331-(April, 2025)]

Exogenous RNA surveillance by proton-sensing TRIM25

Myeonghwan Kim, Youngjoon Pyo, Seong-In Hyun, Minseok Jeong, Yeon Choi, V Narry Kim [Science 388(6742)(April, 2025)]

The biogenesis and regulation of animal microRNAs

Haedong Kim, Young-Yoon Lee, V Narry Kim [Nature Reviews Molecular Cell Biology 26(4), 276-296(April, 2025)]

Cellular dsRNA interactome captured by K1 antibody reveals the regulatory map of exogenous RNA sensing

JinA Lim, Namseok Lee, Seonmin Ju, Jeesoo Kim, Subin Mun, Moonhyeon Jeon, Yong-Ki Lee, Seok-Hoon Lee, Jayoung Ku, Sujin Kim, Sangsu Bae, Jong-Seo Kim, Yoosik Kim [COMMUNICATIONS BIOLOGY 8(1), 389-(March, 2025)]